Analysis of keratin material from the distal digit provides a retrospective window into substance use. This method involves collecting a small clipping, dissolving it, and testing for the presence of parent drugs and metabolites. The resulting data offers a wider detection window than traditional methods such as urine or blood analysis, capturing substance use patterns over several months. For instance, if an individual has used a specific substance regularly over the past six months, the evidence of that use would likely be present in the tested material.
This approach offers distinct advantages in various settings. Its extended detection window is particularly useful in monitoring long-term abstinence in rehabilitation programs, verifying compliance in court-ordered monitoring, and evaluating substance use history in forensic investigations. Historically, the development of this technique provided a valuable alternative when traditional methods were limited by shorter detection times or potential adulteration. Its non-invasive nature also contributes to its acceptability and ease of collection.
