The term references the set of directions provided to individuals collecting saliva samples for the purpose of cortisol analysis. These directions detail the specific steps and precautions necessary to ensure accurate and reliable measurement of cortisol levels in the saliva. Examples include specifying collection times, abstinence from food or drink prior to collection, and proper storage techniques.
Adherence to these guidelines is crucial for obtaining valid cortisol measurements. Deviations from the specified protocol can introduce errors, leading to misinterpretations of an individual’s stress response or endocrine function. Historically, reliance on blood samples was standard practice, but salivary cortisol assessment provides a non-invasive alternative, reducing patient burden and enabling frequent sampling, particularly valuable in research and clinical monitoring of diurnal cortisol patterns.