The detection of psilocybin, the psychoactive compound found in certain fungi, in standard drug screenings is generally unlikely. Common drug tests are designed to identify substances such as opiates, cocaine, amphetamines, PCP, and THC. Psilocybin and its metabolite, psilocin, are not typically included in these panels.
This absence is primarily due to a couple factors. First, psilocybin has a relatively short half-life in the body, meaning it is rapidly metabolized and eliminated. Second, the use of hallucinogenic mushrooms is less prevalent compared to substances commonly screened for in workplace, legal, or medical contexts. Historically, the focus of drug testing has centered on substances associated with addiction, crime, or impaired performance in safety-sensitive roles.